Principal Scientist - Materials Science Job at Pfizer, Groton, CT

  • Pfizer
  • Groton, CT

Job Description

Principal Scientist position in materials science at Pfizer's Groton, Connecticut facility, focusing on solid-form and particle characterization of pharmaceutical compounds. The role involves leading multidisciplinary teams to advance drug molecules from discovery through commercialization using advanced analytical and computational methods.

Responsibilities

  • Lead multidisciplinary project teams as Materials Science Lead to define solid-form and particle design strategies
  • Conduct crystallization screening and evaluation of drug candidate forms for chemical manufacturing compatibility
  • Perform solid-state characterization using X-ray diffraction, spectroscopy, thermal analysis, and particle sizing techniques
  • Apply computational approaches to design experiments and predict crystalline properties of drug substances
  • Oversee external laboratory studies and mentor internal scientists on materials science experimentation

Requirements

  • Ph.D. in Chemistry, Engineering, Materials Science, Pharmaceutics or related field with 5+ years materials science industry experience, OR Master's degree with 10+ years relevant experience
  • Demonstrated expertise in small molecule crystallization and solid-state characterization techniques
  • Experience preparing regulatory submissions and responding to queries on solid form and particle characterization
  • Strong data analysis capabilities and statistical knowledge
  • Excellent oral and written communication skills
  • Proficiency with computational software for predicting pharmaceutical material properties
  • Knowledge of powder and surface characterization methods for pharmaceutical applications

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